Indian Journal of Pharmacy and Pharmacology

Print ISSN: 2393-9079

Online ISSN: 2393-9087

CODEN : IJPPTK

Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, more...


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Original Article


Article page

208-211


Authors Details

Rinkal R. Aware*, Hemant J. Pagar, Ganesh D. Barkade, Shweta Dhawane


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Anticataract activity of pioglitazone by using in-Vitro goat lens model


Original Article

Author Details : Rinkal R. Aware*, Hemant J. Pagar, Ganesh D. Barkade, Shweta Dhawane

Volume : 8, Issue : 3, Year : 2021

Article Page : 208-211

https://doi.org/10.18231/j.ijpp.2021.036



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Abstract

In the present study we have selected antioxidants agents like Pioglitazone and Ascorbic acid were subjected for anti-cataract activity by in vitro glucose induced cataract model. In the procedure, goat lenses was incubated along with the aqueous humor solution containing 55mM glucose with Enalpril as a standard compound and Pioglitazone with varied concentration for the time interval of 72 hours at room temperature. There was a formation of blur layer on the goat eyeball occurs after 10-12 hours and this process complete after 72 hours. The cataract inducing lenses showing higher level of Na, MDA (P<0>


Keywords: Anticataract, Antioxidants, Enalpril, Free radicals, In vitro, Pioglitazone


How to cite : Aware R R, Pagar H J, Barkade G D, Dhawane S, Anticataract activity of pioglitazone by using in-Vitro goat lens model. Indian J Pharm Pharmacol 2021;8(3):208-211

Copyright © 2021 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)







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