Indian Journal of Pharmacy and Pharmacology

Print ISSN: 2393-9079

Online ISSN: 2393-9087

CODEN : IJPPTK

Indian Journal of Pharmacy and Pharmacology (IJPP) an open access, peer-reviewed quarterly journal publishing since 2014 and being published under auspices of the Innovative Education and Scientific Research Foundation (IESRF). The aim of faster and better dissemination of knowledge, we will be publishing article ‘Ahead of Print’ immediately on acceptance. In addition, the journal would allow free access (Open Access) to its contents, which is likely to attract more readers and citations to articles published more...


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207-209


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Vatsala Maheshwari, Pali Rastogi, Pooja Solanki Mishra


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Assessment and analysis of adverse drug reactions in outpatient department of mental hospital of a tertiary care teaching institute of central India


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Author Details : Vatsala Maheshwari, Pali Rastogi, Pooja Solanki Mishra

Volume : 4, Issue : , Year : 2017

Article Page : 207-209


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Abstract

Objective: To monitor and analyze the adverse drug reactions (ADRs) in outpatient department of mental hospital of a tertiary care teaching institute of central India. To assess the causality between drug and adverse reaction using WHO-UMC scale.
Method: A total of 209 adverse drug reactions were recorded in ICSR form obtained from CDSCO website in a period of 6 month from December 2016 to May 2017 in outpatient –department of mental hospital. Causality was assessed according to WHO-UMC causality scale.
Result and Conclusion: Among 209 ADRs recorded 2 ADRs were excluded from further analysis because these were belonging to unlikely category of WHO-UMC causality scale. In this analysis 48.32% ADRs were certain, 32.05% ADRs were probable and 18.66% ADRs were possible. In this analysis 57% cases of ADRs were belonging to male while 43% cases were belonging to female .The maximum ADRs were reported in 21-30 years of age group (35.2%) followed by 31-40 years of age group (27%). The antipsychotics were responsible for maximum ADRs (71.02%), antidepressants were causing 12.07% of ADRs, antiepileptic were causing 14.5% of ADRs, ant manic drugs (lithium) were responsible for 2.4% cases of ADRs. CNS is most commonly affected system (44.92%), followed by metabolic side effects (37.68%).Olanzapine was the most common offending drug and weight gain was the commonest adverse drug reaction.

Keywords: Adverse drug reactions (ADRs), Psychotropic drugs, Analysis, CDSCO, Weight gain, Olanzapine.


How to cite : Maheshwari V, Rastogi P, Mishra P S, Assessment and analysis of adverse drug reactions in outpatient department of mental hospital of a tertiary care teaching institute of central India. Indian J Pharm Pharmacol 2017;4():207-209

Copyright © 2017 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)